The effectiveness of non-pharmacological interventions to treat orthostatic hypotension in people with stroke.
The prevalence of Orthostatic Hypotension (OH) post-stroke is high. OH can be a barrier to stroke rehabilitation, where mobilisation (out-of-bed activities such as sitting, standing and walking) is recommended at the earliest opportunity. The potential risk of harm with OH must be acknowledged and addressed since, in acute and sub-acute stroke, OH has the potential to cause further brain damage due to cerebral hypo-perfusion. This may result in increased disability and mortality. However, current guidelines for the management of people with stroke do not provide guidance on assessing and treating OH.
People with stroke are more likely to have multi-morbidity, thus are at greater risk of polypharmacy. Therefore, identifying non-pharmacological interventions to treat OH is of importance both to minimise polypharmacy, and optimise safe participation in early rehabilitation.
The aim of this systematic review was to summarise the best available evidence regarding the effectiveness of non-pharmacological interventions to treat OH in people with stroke.